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2 edition of Thermophilic actinomycetes and hypersensitivity pneumonitis. found in the catalog.

Thermophilic actinomycetes and hypersensitivity pneumonitis.

Marcus P. Arden Jones

Thermophilic actinomycetes and hypersensitivity pneumonitis.

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  • 10 Currently reading

Published in Bradford .
Written in English


Edition Notes

Ph.D. thesis. Typescript.

SeriesTheses
The Physical Object
Pagination310p.
Number of Pages310
ID Numbers
Open LibraryOL13728150M


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Thermophilic actinomycetes and hypersensitivity pneumonitis. by Marcus P. Arden Jones Download PDF EPUB FB2

Hypersensitivity Pneumonitis. Hypersensitivity pneumonitis reflects a combined abnormality of humoral and cell-mediated immunological responses to organic antigens.

Most cases of HP are caused by thermophilic actinomycetes, but hypersensitivity to Aspergillus spp. is well documented. Upper lobe predominance is the rule and this can be a helpful.

Hypersensitivity pneumonitis is an inflammatory disease of the alveoli caused by hypersensitivity to inhaled organic antigens (Mohr, ). Exposure is commonly occupational and farmers, in particular, are often exposed to molds and fungi in barns leading to the term “Farmer's Lung” (Seal et al., ).

Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma and specifically the alveoli, terminal bronchioli, and. The antigens of hypersensitivity pneumonitis. HP can be provoked by a diverse array of antigens, including bacteria (e.g.

thermophilic actinomycetes), fungi (e.g. Trichosporon cutaneum), animal proteins (e.g. avian) and chemicals (e.g. di-isocyanates) phical, social and occupational factors determine the particular types of HP found throughout the by:   Thermophilic actinomycetes species include Saccharopolyspora rectivirgula (formerly Micropolyspora faeni), Thermoactinomyces vulgaris, Thermoactinomyces viridis, and Thermoactinomyces sacchari, among others.

[] These organisms flourish in areas of high humidity and prefer temperatures of °C. The thermophilic actinomycetes are ubiquitous organisms usually found in contaminated. hypersensitivity pneumonitis INTRODUCTION AND DEFINITION Hypersensitivity pneumonitis (HP), also referred to as Thermophilic actinomycetes and hypersensitivity pneumonitis.

book allergic alveolitis, is a pulmonary disease that occurs due to inhalational exposure to a variety of antigens leading to an inflammatory response of the alveoli and small airways. A scheme has been developed for the identification of thermophilic actinomycetes associated with hypersensitivity pneumonitis.

Eighty strains, 10 Micropolyspora faeni, 6 Saccharomonospora viridis, 52 Thermoactinomyces candidus, 7 T. vulgaris, 4 T. sacchari, and 1 T. dichotomica, either isolated from patients' environment or received as Cited by:   Hypersensitivity Pneumonitis •These dusts can be derived from a variety of sources, such as grain products, animal dander and protein, wood bark, and water Thermophilic actinomycetes and hypersensitivity pneumonitis.

book vaporizers. •The most common antigens are thermophilic Actinomycetes species and avian proteins •The most common diseases are farmer's lung and bird fancier's lung.

Abstract. Thermophilic actinomycetes are the primary sensitizing agents in farmer's lung disease. We compared dilution pour-plate and spread-plate methods for their usefulness in enumerating thermophilic actinomycetes in moldy silage dust and evaluated the ability of a nonquantitative gravity settling technique to recover thermophilic actinomycetes from moldy by: 5.

Hypersensitivity pneumonitis (HP) is a complex syndrome caused by an exaggerated immune response to the inhalation of a large variety of organic particles (1, 2).The disease is characterized by interstitial mononuclear cell infiltration, nonnecrotizing poorly formed granulomas, cellular bronchiolitis, and by: Inhalation exposure to cells and other materials colonized by actinomycetes has been associated with respiratory diseases such as hypersensitivity pneumonitis.

This is particularly evident in agricultural settings where actinomycete exposures are known to play a role in the disease known as Farmer’s Lung. Request PDF | Hypersensitivity Pneumonitis | Hypersensitivity pneumonitis (HP) represents a group of lung disorders caused by the inhalation of a wide variety of.

Hypersensitivity pneumonitis (HP; also called allergic alveolitis, bagpipe lung, or extrinsic allergic alveolitis, EAA) is an inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts.

Sufferers are commonly exposed to the dust by their occupation or hobbies. Hypersensitivity pneumonitis (HP) is categorized as acute, subacute, and chronic based on the. Hypersensitivity pneumonitis (previously called extrinsic allergic alveolitis) is caused by exposure to many inhalable antigens, from the common (such as from birds and mouldy hay) to the exotic (such as from shellfish and silkworm processing).

The particular presentation, investigations, histological findings, and management of the different syndromes recognized are fully covered, including. The most common antigens are thermophilic actinomycetes species and avian proteins.

The most common diseases are farmer's lung and bird fancier's lung. A table listing various hypersensitivity pneumonitis types, sources of exposure, and major antigens is shown. Abstract. In recent years, an increasingly large number of cases of hypersensitivity pneumonitis (HP) have been reported.

Several antigens from bacteria, fungi, protozoa, and birds droppings have been implicated, from a variety of sources including vegetables, Author: Patrick Boiron. This is a report on studies of a hypersensitivity pneumonitis which occurred in 4 out of 27 office workers exposed to a thermophilic actinomycete contaminating the air-conditioning system installed in their office.

All the 4 patients had a history of chronic or episodic respiratory symptoms and they all had symptoms at the time of the initial examination which subsided when they were not at Cited by:   Thermophilic actinomycetes were isolated from (%) of samples of vegetable substrates and soil from different sites in Anambra and Enugu States in actinomyces (Tha.) vulgaris was the most common, occurring in % of samples whileTha.

thalpophilus was isolated from %.Tha. sacchari, Saccharomonospora (Sam.) viridis andSaccharopolyspora (Sap.) Cited by: Correlations were sought between hypersensitivity pneumonitis and exposure to thermophilic actinomycetes in the homes of affected and control subjects in Milwaukee, Wisconsin, during the winter months.

Thermoactinomyces vulgaris was found in 74% of the homes of symptomatic subjects compared with 50% of controls. Precipitating antibodies to T. vulgaris occurred more frequently in the sera of Cited by:   Hypersensitivity pneumonitis (HP) is a worldwide lung disease caused by an immune response to a large variety of inhaled antigens.

Responsible environments contain large quantities of airborne bacteria, fungi, or avian by:   Hypersensitivity pneumonitis is commonly associated with occupational or avocational exposures, such as moldy hay in farmers or bird antigen in bird breeders.

We propose that hypersensitivity pneumonitis may occur in North America, as it. About MyAccess. If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to. Of the questionnaire participants, 50 (48%) reported at least one hypersensitivity pneumonitis (HP)-like symptom (shortness of breath on exertion, flu-like achiness, or fever and chills) in the last 4 weeks; 69 (66%) reported at least one HP-like symptom in the last 12 months.

Actinobacteria (actinomycetes) have been received much attention, as these bacteria produce a variety of natural drugs and other bioactive metabolites. The distribution of actinomycetes in various natural habitats, including soil, ocean, extreme environments, plant, lichens and animals, is described.

The collection and pretreatment of test samples from different sources, design principle of Cited by: 8. About Us. Eurofins EMLab P&K is the leading commercial IAQ laboratory in North America and specializes in analyzing samples to identify mold, bacteria (including Legionella, E.

coli, Endotoxins, etc.), asbestos, and radon. Syn: Hypersitivity Pneumonitis ; Farmer's Lung. Extrinsic allergic alveolitis is a response to inhaled allergens, usually large proteins.

The prototype is "farmer’s lung", caused by the inhalation of thermophilic actinomycetes, notably Saccharopolyspora rectivirgula (formerly Micropolyspora faeni). Jump to Content Jump to Main Navigation.

Home About us Subject Areas Contacts Advanced Search HelpAuthor: Teodor Salmen, Irina Strâmbu. Title:Immunoproteomics for Serological Diagnosis of Hypersensitivity Pneumonitis Caused by Environmental Microorganisms VOLUME: 15 ISSUE: 5 Author(s):Laurence Millon, Gabriel Reboux, Coralie Barrera, Benedicte Rognon, Sandrine Roussel and Michel Monod Affiliation:Department of Parasitology- Mycology, UMR CNRS ChronoEnvironnement, University Hospital – Bd Fleming, Cited by: 8.

More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and school--where we spend as much as 98 percent of our time.

Investigation of hypersensitivity pneumonitis. Interpretation: Precipitating antibodies indicate exposure, and may be found in asymptomatic individuals.

In association with appropriate symptoms, the presence of antibodies supports the diagnosis of hypersensitivity pneumonitis due to the specific agent. To judge from reports in the literature, thermophilic Actinomycetes have proved difficult to isolate.

For isolations from mouldy hay we have developed a convenient method which promises to be. General consideration and implications of the actionomycetales. Taxonomy and classification of the actinomycetes. The fine structure of the actionomycetales.

Genetics of the actinomycetales. The streptomyces spore: Its distinct features and germinal behaviour. Endospores of actinomycetes: Dormancy and germination. Germination of actinomycete spores.

Klote M. Hypersensitive pneumonitis. Allergy and Asthma Proc. Stark PC, Celedon JC, Chew GL, et al. Fungal levels in the home and allergic rhinitis by 5 years of age. chronic hypersensitivity pneumonitis. Can Respir J J Cormier y, Israel-assayag E, Bedard G, Duchaine C.

Hypersensitivity pneumonitis in a peat moss processing plant workers. Am J Respir Crit Care Med ; Metzger F, Haccuria A, Redoux G, Nolard N, Dalphin J-C, DeVuyst P.

Hypersensitivity pneumonitis due to molds in a. To the Editor: Contamination of home or office air conditioners with thermophilic actinomycetes has been reported to cause hypersensitivity pneumonitis.

1 We report here a case of hypersensitivity. Hypersensitivity pneumonitis (HP) is a respiratory disease caused by a delayed immune response to a variety of antigens, primarily consisting of bacteria, fungi and bird proteins. Symptoms include shortness of breath, cough and fever, which occur within hours of exposure to the offending antigen.

Biological, Biochemical, and Biomedical Aspects of Actinomycetes documents the proceedings of the V International Symposium on Actinomycetes Biology held in Oaxtepec, Morelos, Mexico, August Thermophilic Actinomycetes: Their Role in Hypersensitivity PneumonitisBook Edition: 1.

@article{osti_, title = {Isocyanates and respiratory disease: current status}, author = {Musk, A W and Peters, J M and Wegman, D H}, abstractNote = {This paper reviews the known respiratory effects of isocyanates.

There is good evidence to indicate that isocyanates: cause chemical bronchitis/pneumonitis; are potent pulmonary sensitizers capable of causing isocyanate asthma; cause. Role of Thermophilic Actinomycetes in Hypersensitivity Pneumonitis.

A comprehensive study on the environmental occurrence of clinically important thermophilic actinomycetes and on prevalence of precipitating antibodies against them in sera of the exposed subjects has been concluded. Economic Importance of Actinomycetes: The Actinomycetes, forming soil micro-flora have gained the greatest importance in recent years as producers of therapeutic substances.

Many of the Actinomycetes have the ability to synthesize metabolites which hinder the growth of bacteria; these are called antibiotics, and, although harmful to bacteria. • Streptomyces: Aerobe, non-acid fast, rarely causes Actinomycetoma in man.

An imp. Source of antibiotic like Streptomycin. • Thermophilic actinomyces such as Micropolyspora and Thermoactinomyces can cause hypersensitivity pneumonitis (Farmer’s lung and bagassosis) 4.

ACTINOMYCETES • Actinomycetes are branching filamentous bacteria.Actinobacteria, which share the characteristics of both bacteria and fungi, are widely distributed in both terrestrial and aquatic ecosystems, mainly in soil, where they play an essential role in recycling refractory biomaterials by decomposing complex mixtures of polymers in dead plants and animals and fungal materials.

They are considered as the biotechnologically valuable bacteria that are Cited by: This chapter talks about aerobic actinomycetes that are now known to be an evolutionarily heterogeneous assemblage of genera.

At some stage they all form gram-positive rods, and most of the more commonly isolated species exhibit at least rudimentary branching under certain growth conditions; all grow better under aerobic than anaerobic conditions, a feature distinguishing them from most Cited by: